Federal · SAM.gov · Washington, DC

ARPA-H Emerging Health Innovators (EHI) Initiative

Department of Health and Human ServicesIssuing agency·Washington, DC·via the SAM.gov Get Opportunities API

136days left

Due Feb 10, 2027·Posted Sep 25, 2026

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AI takeaways

The ARPA-H Emerging Health Innovators (EHI) Initiative is soliciting proposals from early-career investigators for cutting-edge biomedical, health, and community-engaged research and innovation, with work performed in DC.
Solution Summaries are due October 30, 2026, 2:00 PM ET; Full Proposals are due February 10, 2027, 2:00 PM ET; the total award value shall not exceed $1,050,000.
The initiative covers 16 topic areas including precision control of skin inflammation, deep brain stimulation for sleep exploration, protecting patient data in life science AI, and innovations in biotransport for organ preservation.
The issuing agency is the Advanced Research Projects Agency for Health (ARPA-H), part of the Department of Health and Human Services.
The procurement method is a Solicitation using an Innovative Solutions Opening (ISO), with multiple Other Transaction awards anticipated.
Requirement: Proposers must have an active registration in SAM.gov at the time of proposal submission for their proposal to be determined conforming.
Requirement: Proposal submissions must be led by an early-career principal investigator who is within 8 years after completion of their first terminal degree.
Requirement: Subawardee and consultant costs cannot exceed 30% of the total value of the OT Agreement.
Requirement: All proposers and proposed team members must be employed at a U.S. institution, which includes those in U.S. states and territories.

Est. value: Total Award Value…
Term: 24-month base period and…
Method: Solicitation
Documents: 9 files

These takeaways are AI-generated and may be incomplete or wrong. Always verify every detail against the official documents before you bid.

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Contact the buyer

EHI Program Team

ehi@arpa-h.govEmail

Location:

DC 20003

Open in Maps ↗

Notice

97049f3d1bb44fa292b998d15ce99c6a

ARPA-H-SOL-26-150

Method

Solicitation

Duration

24-month base period and for all research activity. Each proposal must include a plan for an additional 12-month option period

What this bid is asking for

AI-generated

Submit a Solution Summary (2-page anonymized document) by October 30, 2026, describing the proposed solution and its impact.
If encouraged, submit a Full Proposal including a Technical and Management Proposal (max 8 pages), Task Description Document, Milestone Payment Schedule, and Administrative and National Policy Requirements Document by February 10, 2027.
Deliver a 24-month base period of research with quarterly milestones, plus a plan for a 12-month option period (Director's Award), with total costs not exceeding $1,050,000.
Attend an annual in-person meeting and one networking event/workshop per year, and participate in monthly status meetings with the ARPA-H Program Manager.

Requirements

From the documents

Estimated value: Total Award Value shall not exceed $1,050,000

Posted Scope of Work

innovators and their organizations to develop cutting-edge biomedical, health, and community-engaged research and innovation. ARPA-H anticipates multiple Other Transaction awards resulting from this announcement

Amendment 1: This amendment clarifies the number of submissions that may be submitted by each offeror. See section 2.4 of the ISO. It also updates the solution summary cover sheet and the FAQ.

Scope, read from the documentsAI-generated

The EHI Initiative seeks proposals from early-career investigators across 16 topic areas, including precision control of skin inflammation, internal sensing and targeted control of inflammation, deep brain stimulation for mechanistic sleep exploration, restoring the brain's drainage and immune balance after injury, host-pathway interventions for neurotropic disease, protecting patient data in life science AI, engineering DRT for programmable DNA synthesis, prevention of lethal alpha-gal allergic responses, smart microbiome-informed lesion and enamel restoration, ending preventable deaths from ectopic pregnancy, transforming the well-woman exam, innovations in biotransport for long-term preservation of tissues and organs, next-generation human tissue platforms, near real-time non-contact determination of sterility, implantable systems for local cancer control, and causally-grounded alignment for clinical generative AI tools. Proposals must cover a 24-month base period with an additional 12-month option period. The program includes a two-step submission process: a Solution Summary followed by a Full Proposal.

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Documents

Download zip

EHI Administrative FAQ Sep 25 2026.docxDOCX

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EHI ISO 2026_ARPA-H-SOL-26-150_Amendment 1.pdfPDF

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Attachment A_Solution Summary_Amendment 1.docxDOCX

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Attachment B_Pitch Slides.pptxPPTX

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Attachment G_ARPA-H Model Other Transaction.docxDOCX

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Attachment C_Technical and Management Proposal.docxDOCX

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Attachment F_Administrative_National_Policy_Requirement.docxDOCX

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Attachment D_Task Description Document (TDD).docxDOCX

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Attachment E_Milestone_Payment_Schedule.docxDOCX

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Questions & answers

AI-generated

What is the total award value?

Total Award Value shall not exceed $1,050,000.

When are Solution Summaries due?

Solution Summaries Due: October 30, 2026, 2:00 PM ET.

When are Full Proposals due?

Full Proposals Due: February 10, 2027, 2:00 PM ET.

Who can be a Project Lead?

Proposal submissions must be led by an early-career principal investigators (academic, non-profit, industry etc.) who is within 8 years after completion of their first terminal degree.

What is the submission process?

The EHI Initiative uses a two-step submission process: Step 1: Solution Summary Submission, and Step 2: Full Proposal Submission.

Full source recordEvery field SAM.gov published, untouched

Hit

97049f3d1bb44fa292b998d15ce99c6a

Type

Code: o
Value: Solicitation

Type

opportunity

Award

Awardee

Title

ARPA-H Emerging Health Innovators (EHI) Initiative

R Score

Is Active

Yes

Is Canceled

Publish Date

Sep 25, 2026

Descriptions

Content: <p>The Advanced Research Projects Agency for Health (ARPA-H) Emerging Health Innovators (EHI) aims to or seeks to ensure ARPA-H identifies and engages early career investigators. To achieve this goal, ARPA-H is soliciting proposals from these re
Last Modified Date: Sep 25, 2026

Modified Date

Sep 25, 2026

Response Date

Feb 10, 2027

Modifications

Count: 2

Parent Notice Id

a8cdbf8d37ca4b7db3e81f32b8fb96fe

Response Time Zone

America/New_York

Response Date Actual

Feb 10, 2027

Solicitation Number

ARPA-H-SOL-26-150

Organization Hierarchy

Code

7500

Name

HEALTH AND HUMAN SERVICES, DEPARTMENT OF

Type

DEPARTMENT

Level

Status

active

Address

Zip: "20201"
City: "Washington"
State: "DC"
Country: "US"
Street Address: "Hubert H. Humphrey Building 200 Independence Avenue, SW "

Organization Id

100004222

Code

7529

Name

NATIONAL INSTITUTES OF HEALTH

Type

AGENCY

Level

Status

active

Address

Zip: "20892"
City: "Bethesda"
State: "MD"
Country: "US"
Street Address: "3100 Center Drive Room 1B59"

Organization Id

100019747

Code

75N992

Name

NIH ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)

Type

OFFICE

Level

Status

active

Address

Zip: "208920004"
City: "Bethesda"
State: "MD"
Country: "USA"
Street Address: "BG NIHBC 01 Room 228"
Street Address2: "1 Center Drive"

Organization Id

500183629

Type

Solicitation

Title

ARPA-H Emerging Health Innovators (EHI) Initiative

Active

Yes

Detail

Type

Naics

Code: 541714
Type: primary

Title

ARPA-H Emerging Health Innovators (EHI) Initiative

Archive

Date: Feb 25, 2027
Type: auto15

Version

Permissions

IVL

Read: Yes
Create: Yes
Delete: Yes
Update: Yes

Solicitation

Set Aside

NONE

Deadlines

Response: Feb 10, 2027
Response Tz: America/New_York

Organization Id

500183629

Point Of Contact

Type: primary
Email: EHI@arpa-h.gov
Full Name: EHI Program Team

Classification Code

AN41

Place Of Performance

Zip

20003

State

Code: DC
Name: District of Columbia

Country

Code: USA
Name: UNITED STATES

Solicitation Number

ARPA-H-SOL-26-150

Additional Reporting

none

Ui Link

https://sam.gov/opp/97049f3d1bb44fa292b998d15ce99c6a/view

History

Links

Self

Href: https://86samdotgovopportunitiesmodern.prod.apps-internal.prod-iae.bsp.gsa.gov/opps/v2/opportunities/97049f3d1bb44fa292b998d15ce99c6a/history{?postedFrom}
Templated: Yes

History

Index: 4
Title: ARPA-H Emerging Health Innovators (EHI) Initiative
Latest: 1
Deleted: 0
Action Date: 2026-09-25T17:22:39.469+00
Action Type: publish
Posted Date: 2026-09-25T17:22:39.465+00
Request Type: modify
Cancel Notice: 0
Archive Notice: 0
Opportunity Id: 97049f3d1bb44fa292b998d15ce99c6a
Procurement Type: o
Solicitation Number: ARPA-H-SOL-26-150
Parent Opportunity Id: a8cdbf8d37ca4b7db3e81f32b8fb96fe
Related Opportunity Id: 061df5c2d86640f2a4c11101e810e453

Index: 3
Title: ARPA-H Emerging Health Innovators (EHI) Initiative
Latest: 0
Deleted: 0
Action Date: 2026-09-15T17:16:39.729+00
Action Type: publish
Posted Date: 2026-09-15T17:16:39.726+00
Request Type: modify
Cancel Notice: 0
Archive Notice: 0
Opportunity Id: 0c197a6d9c50443db7e1a1949ba5256e
Procurement Type: o
Solicitation Number: ARPA-H-SOL-26-150
Parent Opportunity Id: a8cdbf8d37ca4b7db3e81f32b8fb96fe
Related Opportunity Id: 061df5c2d86640f2a4c11101e810e453

Index: 2
Title: ARPA-H Emerging Health Innovators (EHI) Initiative Proposers Day
Latest: 0
Deleted: 0
Action Date: 2026-09-15T17:15:56.469+00
Action Type: publish
Posted Date: 2026-09-15T17:15:56.465+00
Request Type: submit
Cancel Notice: 0
Archive Notice: 0
Opportunity Id: a8cdbf8d37ca4b7db3e81f32b8fb96fe
Procurement Type: o
Solicitation Number: ARPA-H-SOL-26-150
Related Opportunity Id: 061df5c2d86640f2a4c11101e810e453

Index: 1
Title: ARPA-H Emerging Health Innovators (EHI) Initiative Proposers Day
Latest: 1
Deleted: 0
Action Date: 2026-09-08T13:18:47.865+00
Action Type: publish
Posted Date: 2026-09-08T13:18:47.862+00
Request Type: submit
Cancel Notice: 0
Archive Notice: 0
Opportunity Id: 061df5c2d86640f2a4c11101e810e453
Procurement Type: s
Solicitation Number: ARPA-H-SN-26-161

Base Type

Solicitation

Notice Id

97049f3d1bb44fa292b998d15ce99c6a

Naics Code

541714

Resources

Attachments

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Size: 44526
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Deleted Flag: "0"
Access Status: "public"
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Explicit Access: "0"
Attachment Order: 12
Export Controlled: "0"

Name: "EHI ISO 2026_ARPA-H-SOL-26-150_Amendment 1.pdf"
Size: 428118
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Name: "Attachment A_Solution Summary_Amendment 1.docx"
Size: 45997
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Name: "Attachment G_ARPA-H Model Other Transaction.docx"
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Name: "EHI ISO 2026_ARPA-H-SOL-26-150_clean_Sep 15.pdf"
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Opportunity Id

97049f3d1bb44fa292b998d15ce99c6a

Department

DEPARTMENT OF HEALTH AND HUMAN SERVICES

Posted Date

Sep 25, 2026

Detail Fetched

Yes

Resource Links

History Fetched

Yes

Point Of Contact

Type: primary
Email: EHI@arpa-h.gov
Full Name: EHI Program Team

Description Text

The Advanced Research Projects Agency for Health (ARPA-H) Emerging Health Innovators (EHI) aims to or seeks to ensure ARPA-H identifies and engages early career investigators. To achieve this goal, ARPA-H is soliciting proposals from these researchers and innovators and their organizations to develop cutting-edge biomedical, health, and community-engaged research and innovation. ARPA-H anticipates multiple Other Transaction awards resulting from this announcement Amendment 1: This amendment clarifies the number of submissions that may be submitted by each offeror. See section 2.4 of the ISO. It also updates the solution summary cover sheet and the FAQ.

Resources Fetched

Yes

Response Dead Line

Feb 10, 2027

Full Parent Path Name

DEPARTMENT OF HEALTH AND HUMAN SERVICES.NATIONAL INSTITUTES OF HEALTH.NIH ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)

Place Of Performance

Zip

20003

State

Code: DC
Name: District of Columbia

Country

Code: USA
Name: UNITED STATES

Solicitation Number

ARPA-H-SOL-26-150

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Source: SAM.gov (notice 97049f3d1bb44fa292b998d15ce99c6a), retrieved via the SAM.gov Get Opportunities API. View the official posting, and always confirm requirements and deadlines with the issuing agency.

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Federal · SAM.gov · Washington, DC

ARPA-H Emerging Health Innovators (EHI) Initiative

Department of Health and Human ServicesIssuing agency·Washington, DC·via the SAM.gov Get Opportunities API

136days left

Due Feb 10, 2027·Posted Sep 25, 2026

Prequalify For BondingBonding Prequal

AI takeaways

The ARPA-H Emerging Health Innovators (EHI) Initiative is soliciting proposals from early-career investigators for cutting-edge biomedical, health, and community-engaged research and innovation, with work performed in DC.
Solution Summaries are due October 30, 2026, 2:00 PM ET; Full Proposals are due February 10, 2027, 2:00 PM ET; the total award value shall not exceed $1,050,000.
The initiative covers 16 topic areas including precision control of skin inflammation, deep brain stimulation for sleep exploration, protecting patient data in life science AI, and innovations in biotransport for organ preservation.
The issuing agency is the Advanced Research Projects Agency for Health (ARPA-H), part of the Department of Health and Human Services.
The procurement method is a Solicitation using an Innovative Solutions Opening (ISO), with multiple Other Transaction awards anticipated.
Requirement: Proposers must have an active registration in SAM.gov at the time of proposal submission for their proposal to be determined conforming.
Requirement: Proposal submissions must be led by an early-career principal investigator who is within 8 years after completion of their first terminal degree.
Requirement: Subawardee and consultant costs cannot exceed 30% of the total value of the OT Agreement.
Requirement: All proposers and proposed team members must be employed at a U.S. institution, which includes those in U.S. states and territories.

Est. value: Total Award Value…
Term: 24-month base period and…
Method: Solicitation
Documents: 9 files

These takeaways are AI-generated and may be incomplete or wrong. Always verify every detail against the official documents before you bid.

Want to know if you can be bonded for this project? Get prequalified.Estimated at $1.05M. One free application, soft pull — sized to your work.

Know you can be bonded before you spend a week on the bid
No scramble for a bond at the deadline — it becomes a request form
A good guy letter to show an agency

Prequalify For Bonding →

Contact the buyer

EHI Program Team

ehi@arpa-h.govEmail

Location:

DC 20003

Open in Maps ↗

Notice

97049f3d1bb44fa292b998d15ce99c6a

ARPA-H-SOL-26-150

Method

Solicitation

Duration

24-month base period and for all research activity. Each proposal must include a plan for an additional 12-month option period

What this bid is asking for

AI-generated

Submit a Solution Summary (2-page anonymized document) by October 30, 2026, describing the proposed solution and its impact.
If encouraged, submit a Full Proposal including a Technical and Management Proposal (max 8 pages), Task Description Document, Milestone Payment Schedule, and Administrative and National Policy Requirements Document by February 10, 2027.
Deliver a 24-month base period of research with quarterly milestones, plus a plan for a 12-month option period (Director's Award), with total costs not exceeding $1,050,000.
Attend an annual in-person meeting and one networking event/workshop per year, and participate in monthly status meetings with the ARPA-H Program Manager.

Requirements

From the documents

Estimated value: Total Award Value shall not exceed $1,050,000

Posted Scope of Work

Amendment 1: This amendment clarifies the number of submissions that may be submitted by each offeror. See section 2.4 of the ISO. It also updates the solution summary cover sheet and the FAQ.

Scope, read from the documentsAI-generated

More science & technology research bids in Washington, DC, weekly.

We post new science & technology research opportunities in Washington, DC as agencies publish them. Get them in one email — free, and unsubscribe whenever.

Documents

Download zip

EHI Administrative FAQ Sep 25 2026.docxDOCX

Preview Download

EHI ISO 2026_ARPA-H-SOL-26-150_Amendment 1.pdfPDF

Preview Download

Attachment A_Solution Summary_Amendment 1.docxDOCX

Preview Download

Attachment B_Pitch Slides.pptxPPTX

Preview Download

Attachment G_ARPA-H Model Other Transaction.docxDOCX

Preview Download

Attachment C_Technical and Management Proposal.docxDOCX

Preview Download

Attachment F_Administrative_National_Policy_Requirement.docxDOCX

Preview Download

Attachment D_Task Description Document (TDD).docxDOCX

Preview Download

Attachment E_Milestone_Payment_Schedule.docxDOCX

Preview Download

Questions & answers

AI-generated

What is the total award value?

Total Award Value shall not exceed $1,050,000.

When are Solution Summaries due?

Solution Summaries Due: October 30, 2026, 2:00 PM ET.

When are Full Proposals due?

Full Proposals Due: February 10, 2027, 2:00 PM ET.

Who can be a Project Lead?

Proposal submissions must be led by an early-career principal investigators (academic, non-profit, industry etc.) who is within 8 years after completion of their first terminal degree.

What is the submission process?

The EHI Initiative uses a two-step submission process: Step 1: Solution Summary Submission, and Step 2: Full Proposal Submission.

Full source recordEvery field SAM.gov published, untouched

Hit

97049f3d1bb44fa292b998d15ce99c6a

Type

Code: o
Value: Solicitation

Type

opportunity

Award

Awardee

Title

ARPA-H Emerging Health Innovators (EHI) Initiative

R Score

Is Active

Yes

Is Canceled

Publish Date

Sep 25, 2026

Descriptions

Content: <p>The Advanced Research Projects Agency for Health (ARPA-H) Emerging Health Innovators (EHI) aims to or seeks to ensure ARPA-H identifies and engages early career investigators. To achieve this goal, ARPA-H is soliciting proposals from these re
Last Modified Date: Sep 25, 2026

Modified Date

Sep 25, 2026

Response Date

Feb 10, 2027

Modifications

Count: 2

Parent Notice Id

a8cdbf8d37ca4b7db3e81f32b8fb96fe

Response Time Zone

America/New_York

Response Date Actual

Feb 10, 2027

Solicitation Number

ARPA-H-SOL-26-150

Organization Hierarchy

Code

7500

Name

HEALTH AND HUMAN SERVICES, DEPARTMENT OF

Type

DEPARTMENT

Level

Status

active

Address

Zip: "20201"
City: "Washington"
State: "DC"
Country: "US"
Street Address: "Hubert H. Humphrey Building 200 Independence Avenue, SW "

Organization Id

100004222

Code

7529

Name

NATIONAL INSTITUTES OF HEALTH

Type

AGENCY

Level

Status

active

Address

Zip: "20892"
City: "Bethesda"
State: "MD"
Country: "US"
Street Address: "3100 Center Drive Room 1B59"

Organization Id

100019747

Code

75N992

Name

NIH ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)

Type

OFFICE

Level

Status

active

Address

Zip: "208920004"
City: "Bethesda"
State: "MD"
Country: "USA"
Street Address: "BG NIHBC 01 Room 228"
Street Address2: "1 Center Drive"

Organization Id

500183629

Type

Solicitation

Title

ARPA-H Emerging Health Innovators (EHI) Initiative

Active

Yes

Detail

Type

Naics

Code: 541714
Type: primary

Title

ARPA-H Emerging Health Innovators (EHI) Initiative

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ARPA-H Emerging Health Innovators (EHI) Initiative

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Requirements

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ARPA-H Emerging Health Innovators (EHI) Initiative

What this bid is asking for

Requirements

Posted Scope of Work

More science & technology research bids in Washington, DC, weekly.

Documents

Sign up for a Light RFP account to download documents

Questions & answers

Need a bond for this one? Get prequalified once.

Not the right RFP for you?