National Institutes of HealthIssuing agency·Nationwide·via the Grants.gov Search APININDS intends to support a Diagnostic Research Innovation Center (DRIC) for the next phase of the Undiagnosed Diseases Network (UDN). The new Network is expected to include a Clinical and Data Coordinating Center (CDCC), geographically distributed clinical Networks of Diagnostic Excellence (NODEs), the NIH Undiagnosed Diseases Program (UDP), a DRIC, the UDN Foundation, patient advocacy organizations, NIH, and other stakeholders. The DRIC will contribute to the diagnosis of UDN participants, including participating in the systematic re-evaluation of unsolved UDN cases from previous phases of the UDN.
The DRIC is expected to test and advance innovative, new diagnostic tools and strategies for both genomic and non-genomic conditions. Working closely with clinical NODEs, the UDP, the CDCC, and other UDN stakeholders, the DRIC will support the generation and testing of diagnostic hypotheses including providing expertise and resources in advanced sequencing and multi-omics, gene function studies in animal and human in vitro models, and the development of non-genetic diagnostic strategies. Collaborating with the Network, the DRIC will contribute to the discovery of novel disease-associated genes and genomic variants, non-genetic contributors to UDN phenotypes, and the identification of new diseases and syndromes. Support is expected for an integrated center that brings together complementary capabilities and investigators with demonstrated scientific synergy and prior collaboration.
Applications are not being solicited at this time. This Forecast is being published to provide potential applicants time to plan, establish collaborations, and develop responsive projects.
The DRIC will contribute to the diagnosis of UDN participants, including participating in the systematic re-evaluation of unsolved UDN cases from previous phases. It will test and advance innovative, new diagnostic tools and strategies for both genomic and non-genomic conditions. Working with clinical NODEs, the UDP, the CDCC, and other UDN stakeholders, the DRIC will support the generation and testing of diagnostic hypotheses, including providing expertise and resources in advanced sequencing and multi-omics, gene function studies in animal and human in vitro models, and the development of non-genetic diagnostic strategies. It will contribute to the discovery of novel disease-associated genes and genomic variants, non-genetic contributors to UDN phenotypes, and the identification of new diseases and syndromes.
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"25""Others (see text field entitled \"Additional Information on Eligibility\" for clarification)""22""For profit organizations other than small businesses""01""County governments""05""Independent school districts""13""Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education""02""City or township governments""04""Special district governments""00""State governments""06""Public and State controlled institutions of higher education""23""Small businesses""07""Native American tribal governments (Federally recognized)""08""Public housing authorities/Indian housing authorities""20""Private institutions of higher education""11""Native American tribal organizations (other than Federally recognized tribal governments)""12""Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education""CA""Cooperative Agreement""HL""Health"Most public work asks for the two below, and the solicitation documents are where it’s stated. Here’s what each costs through Light RFP if you need one.
Source: Grants.gov (opportunity 363837), retrieved via the Grants.gov Search API. View the official posting, and always confirm requirements and deadlines with the issuing agency.