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The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission through the continued support of the Collaborative Network for Clinical Research on Immune Tolerance. The purpose of this program is to enhance understanding of the underlying mechanisms of the induction, maintenance, and loss of immune tolerance in humans; and to develop improved tolerogenic interventions for the prevention and treatment of immune system mediated diseases (including transplant rejection, autoimmune diseases, and asthma and allergic diseases). The three major scientific goals include: 1) conduct clinical trials to determine the safety and efficacy of promising tolerogenic strategies in liver, kidney and pancreatic islet transplantation; allergic diseases and asthma; and autoimmune diseases; 2) investigate the basic mechanisms of immune tolerance in these diseases as an integral part of clinical trials; and 3) develop, refine and validate immune assays to monitor the induction, maintenance, and loss of tolerance in these disorders.
Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
The program's three major scientific goals include: 1) conduct clinical trials to determine the safety and efficacy of promising tolerogenic strategies in liver, kidney and pancreatic islet transplantation; allergic diseases and asthma; and autoimmune diseases; 2) investigate the basic mechanisms of immune tolerance in these diseases as an integral part of clinical trials; and 3) develop, refine and validate immune assays to monitor the induction, maintenance, and loss of tolerance in these disorders.
"02""City or township governments""06""Public and State controlled institutions of higher education""07""Native American tribal governments (Federally recognized)""12""Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education""25""Others (see text field entitled \"Additional Information on Eligibility\" for clarification)""23""Small businesses""13""Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education""20""Private institutions of higher education""22""For profit organizations other than small businesses""11""Native American tribal organizations (other than Federally recognized tribal governments)""08""Public housing authorities/Indian housing authorities""05""Independent school districts""01""County governments""04""Special district governments""00""State governments""CA""Cooperative Agreement""HL""Health"Source: Grants.gov (opportunity 362946), retrieved via the Grants.gov Search API. View the official posting , always confirm requirements and deadlines with the issuing agency.