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This Notice of Funding Opportunity (NOFO) announces the restructured Shared Instrumentation Grant (SIG) Program that consolidates three existing shared-use instrumentation programs, i.e., the Shared Instrumentation Grant program, the High-End Instrumentation Grant program, and the Basic Instrumentation Grant program. The NOFO invites applications from groups of NIH-supported investigators to purchase or upgrade a single state-of-the-art commercially available instrument or an integrated instrumentation system. The instruments purchased through the SIG Program are required to be optimally shared among the users to ensure efficient and cost-effective research operations, enable rigorous and reproducible measurements, and encourage collaborative research and benefit broad research communities at large. The minimum award is $300,000. There is no cap on the total cost of the instrument; however, the maximum award is $5,000,000. Cost sharing is required for premium instruments or special use instruments.
"12""Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education""06""Public and State controlled institutions of higher education""20""Private institutions of higher education""13""Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education""G""Grant""HL""Health""04""Special district governments""12""Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education""22""For profit organizations other than small businesses""25""Others (see text field entitled \"Additional Information on Eligibility\" for clarification)""02""City or township governments""11""Native American tribal organizations (other than Federally recognized tribal governments)""08""Public housing authorities/Indian housing authorities""13""Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education""07""Native American tribal governments (Federally recognized)""01""County governments""06""Public and State controlled institutions of higher education""23""Small businesses""20""Private institutions of higher education""00""State governments""05""Independent school districts""G""Grant""HL""Health""NIH""HHS-NIH11""HHS-NIH11""National Institutes of Health""HHS""HHS""HHS""HHS""Department of Health and Human Services""HHS"{"id":431030,"revision":2,"cfdaNumber":"93.351","programTitle":"Research Infrastructure Programs","opportunityId":360532}10{"revision":0,"opportunityId":360532}"Jun 25, 2026 12:49:40 PM EDT""U""HHS-NIH11""300000"2027true"Sep 08, 2025 09:05:32 AM EDT""Sep 08, 2025 12:00:00 AM EDT""5000000""Mar 01, 2027 12:00:00 AM EST""<p>This Notice of Funding Opportunity (NOFO) announces the restructured Shared Instrumentation Grant (SIG) Program that consolidates three existing shared-use instrumentation programs, i.e., the Shared Instrumentation Grant program, the High-End Instrumentation Grant program, and the Basic Instrumentation Grant program. The NOFO invites applications from groups of NIH-supported investigators to purchase or upgrade a single item of state-of-the-art commercially available instrument or an integrated instrumentation system. The instruments purchased through the SIG Program require to be optimally shared among the users to ensure efficient and cost-effective research operations, enable rigorous and reproducible measurements, and encourage collaborative research and benefit broad research communities at large. The minimum award is $300,000. There is no cap on total cost of the instrument; however, the maximum award is $5,000,000. Cost sharing is required for premium instruments or special use instruments. </p>"{"code":"NIH","seed":"HHS-NIH11","agencyCode":"HHS-NIH11","agencyName":"National Institutes of Health","topAgencyCode":"HHS"}360532[{"id":"13","description":"Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"20","description":"Private institutions of higher education"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"06","description":"Public and State controlled institutions of higher education"}]"102""2025-09-08-00-00-00""Sep 08, 2025 09:05:32 AM EDT""2027-03-01-00-00-00""Sep 08, 2025 09:05:32 AM EDT""83000000""Xiang-Ning Li, MD, PhD""xiang-ning.li@nih.gov""301-435-1744""2025-09-08-09-05-32"[{"id":"G","description":"Grant"}]"300,000""Mar 01, 2027 12:00:00 AM EST""5,000,000""xiang-ning.li@nih.gov""2027-03-01-00-00-00""Dec 12, 2025 12:00:00 AM EST""2025-12-12-00-00-00""83,000,000"[{"id":"HL","description":"Health"}]"Jul 01, 2026 12:00:00 AM EDT""2026-07-01-00-00-00"0360532"D""Discretionary"{"id":431030,"revision":2,"cfdaNumber":"93.351","programTitle":"Research Infrastructure Programs","opportunityId":360532}21{"revision":1,"opportunityId":360532}"N""Jun 25, 2026 12:53:38 PM EDT""U""HHS-NIH11""300000"2027true"Sep 08, 2025 09:05:32 AM EDT""Updated Opportunity Number to match NOFO.""Sep 08, 2025 12:00:00 AM EDT""5000000""Mar 01, 2027 12:00:00 AM EST""<p>This Notice of Funding Opportunity (NOFO) announces the restructured Shared Instrumentation Grant (SIG) Program that consolidates three existing shared-use instrumentation programs, i.e., the Shared Instrumentation Grant program, the High-End Instrumentation Grant program, and the Basic Instrumentation Grant program. The NOFO invites applications from groups of NIH-supported investigators to purchase or upgrade a single item of state-of-the-art commercially available instrument or an integrated instrumentation system. The instruments purchased through the SIG Program require to be optimally shared among the users to ensure efficient and cost-effective research operations, enable rigorous and reproducible measurements, and encourage collaborative research and benefit broad research communities at large. The minimum award is $300,000. There is no cap on total cost of the instrument; however, the maximum award is $5,000,000. Cost sharing is required for premium instruments or special use instruments. </p>"{"code":"NIH","seed":"HHS-NIH11","agencyCode":"HHS-NIH11","agencyName":"National Institutes of Health","topAgencyCode":"HHS"}360532[{"id":"13","description":"Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"20","description":"Private institutions of higher education"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"06","description":"Public and State controlled institutions of higher education"}]"102""2025-09-08-00-00-00""Jun 25, 2026 12:49:40 PM EDT""2027-03-01-00-00-00""Jun 25, 2026 12:49:40 PM EDT""83000000""Xiang-Ning Li, MD, PhD""xiang-ning.li@nih.gov""301-435-1744""2026-06-25-12-49-40"[{"id":"G","description":"Grant"}]"300,000""Mar 01, 2027 12:00:00 AM EST""5,000,000""xiang-ning.li@nih.gov""2027-03-01-00-00-00""Dec 12, 2025 12:00:00 AM EST""2025-12-12-00-00-00""83,000,000"[{"id":"HL","description":"Health"}]"Jul 01, 2026 12:00:00 AM EDT""2026-07-01-00-00-00"1360532"D""Discretionary"{"id":434311,"revision":2,"cfdaNumber":"93.310","programTitle":"Trans-NIH Research Support","opportunityId":360532}{"id":431030,"revision":2,"cfdaNumber":"93.351","programTitle":"Research Infrastructure Programs","opportunityId":360532}{"id":434310,"revision":2,"cfdaNumber":"93.855","programTitle":"Allergy and Infectious Diseases Research","opportunityId":360532}{"id":434313,"revision":2,"cfdaNumber":"93.859","programTitle":"Biomedical Research and Research Training","opportunityId":360532}{"id":434314,"revision":2,"cfdaNumber":"93.866","programTitle":"Aging Research","opportunityId":360532}{"id":434312,"revision":2,"cfdaNumber":"93.867","programTitle":"Vision Research","opportunityId":360532}33{"revision":3,"opportunityId":360532}"Jun 25, 2026 12:53:38 PM EDT""U""HHS-NIH11""300000"2027true"Sep 08, 2025 09:05:32 AM EDT""Updated Opportunity Number to match NOFO.""Sep 08, 2025 12:00:00 AM EDT""5000000""Mar 01, 2027 12:00:00 AM EST""<p>This Notice of Funding Opportunity (NOFO) announces the restructured Shared Instrumentation Grant (SIG) Program that consolidates three existing shared-use instrumentation programs, i.e., the Shared Instrumentation Grant program, the High-End Instrumentation Grant program, and the Basic Instrumentation Grant program. The NOFO invites applications from groups of NIH-supported investigators to purchase or upgrade a single item of state-of-the-art commercially available instrument or an integrated instrumentation system. The instruments purchased through the SIG Program require to be optimally shared among the users to ensure efficient and cost-effective research operations, enable rigorous and reproducible measurements, and encourage collaborative research and benefit broad research communities at large. The minimum award is $300,000. There is no cap on total cost of the instrument; however, the maximum award is $5,000,000. Cost sharing is required for premium instruments or special use instruments. </p>"{"code":"NIH","seed":"HHS-NIH11","agencyCode":"HHS-NIH11","agencyName":"National Institutes of Health","topAgencyCode":"HHS"}360532[{"id":"13","description":"Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"20","description":"Private institutions of higher education"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"06","description":"Public and State controlled institutions of higher education"}]"102""2025-09-08-00-00-00""Jun 25, 2026 12:53:38 PM EDT""2027-03-01-00-00-00""Jun 25, 2026 12:53:38 PM EDT""83000000""Xiang-Ning Li, MD, PhD""xiang-ning.li@nih.gov""301-435-1744""2026-06-25-12-53-38"[{"id":"G","description":"Grant"}]"300,000""Mar 01, 2027 12:00:00 AM EST""5,000,000""xiang-ning.li@nih.gov""2027-03-01-00-00-00""Dec 12, 2025 12:00:00 AM EST""2025-12-12-00-00-00""83,000,000"[{"id":"HL","description":"Health"}]"Jul 01, 2026 12:00:00 AM EDT""2026-07-01-00-00-00"3360532"D""Discretionary"{"id":353389,"fileName":"PAR-27-022-Full-Announcement.html","mimeType":"text/html;charset=UTF-8","createdDate":"Jun 25, 2026 12:53:51 PM EDT","fileLobSize":142184,"opportunityId":360532,"fileDescription":"PAR-27-022-Full-Announcement.html","synopsisAttFolderId":80472}Source: Grants.gov (opportunity GRANTS-360532), retrieved via the Grants.gov Search API. 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