Generate a quick AI overview of this bid, pulled from its details and the attached documents.
The Office of Research Infrastructure Programs (ORIP) encourages grant applications aimed at developing, characterizing, or improving research models of human health and diseases; developing biology based new approach methodologies (NAMs) applicable to human health and diseases; or improving access to information about or generated from the use of models of human disease. The models, including NAMs, and related biological materials developed must be broadly applicable to the scientific interests of two or more NIH Institutes or Centers (ICs) and must evaluate diseases and processes that impact multiple organ systems in order to align with the ORIP"s NIH-wide mission and programs. Applications must describe the need for and the potential impact of the proposed resources on the research community across a range of scientific disciplines supported by multiple NIH ICs. Applications to develop models that relate strictly to a specific disease or a select area of research or that do not have a broad impact on the NIH-wide research community will not be accepted. Projects that predominantly address the research interests of one NIH IC but are only peripherally related to the research interests of other ICs will also not be accepted, if submitted in response to this notice of funding opportunity (NOFO).
"06""Public and State controlled institutions of higher education""01""County governments""11""Native American tribal organizations (other than Federally recognized tribal governments)""12""Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education""22""For profit organizations other than small businesses""00""State governments""07""Native American tribal governments (Federally recognized)""23""Small businesses""20""Private institutions of higher education""G""Grant""HL""Health""06""Public and State controlled institutions of higher education""01""County governments""25""Others (see text field entitled \"Additional Information on Eligibility\" for clarification)""12""Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education""02""City or township governments""22""For profit organizations other than small businesses""00""State governments""07""Native American tribal governments (Federally recognized)""13""Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education""23""Small businesses""20""Private institutions of higher education""G""Grant""HL""Health""NIH""HHS-NIH11""HHS-NIH11""National Institutes of Health""HHS""HHS""HHS""HHS""Department of Health and Human Services""HHS"{"id":429511,"revision":3,"cfdaNumber":"93.351","programTitle":"Research Infrastructure Programs","opportunityId":359648}10{"revision":0,"opportunityId":359648}"Y""Dec 05, 2025 01:31:04 PM EST""U""HHS-NIH11"2027false"Jun 09, 2025 03:33:00 PM EDT""Jun 09, 2025 12:00:00 AM EDT""Oct 01, 2026 12:00:00 AM EDT""<p>The Division of Program Coordination, Planning and Strategic Initiatives, Office of Research Infrastructure Programs (<a href=\"https://orip.nih.gov/\" target=\"_blank\" style=\"color: rgb(31, 107, 178);\">ORIP</a>) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications aimed at developing, characterizing, or improving research models of human health and diseases; developing biology based new approach methodologies (NAMs); or improving access to information about or generated from the use of models of human disease. The models, including NAMs, and related biological materials developed must be broadly applicable to the scientific interests of two or more NIH Institutes or Centers (ICs) and must evaluate diseases and processes that impact multiple organ systems in order to align with the ORIP’s NIH-wide mission and programs. Applications must describe the need for and the potential impact of the proposed resources on the research community across a range of scientific disciplines supported by multiple NIH ICs.</p>\n<p><br></p>\n<p>This NOFO will utilize the R24 activity code to support research projects that will enhance the capability of resources to serve biomedical research. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. Details of the planned NOFO are provided below.</p>\n<p><br></p>\n<p><strong>Research Initiative Details</strong></p>\n<p>ORIP’s intent with this NOFO is to support resource-related research projects aimed at developing and characterizing new model resources, improving existing resources, developing NAMs, or acquiring deep understanding of a model system to improve the utilization, accessibility, and translational value of experimental research models to the research community. An application may be predominantly research based if that research potentially leads to the development of tools or resources that will have a broad impact on the biomedical research community. An application also may be aimed at final development or enhancement of existing resources. Applications should:</p>\n<ul>\n <li>Demonstrate the need for the proposed resources or technologies/tools.</li>\n <li>Address the impact, benefit, utilization, distribution, and accessibility of the proposed resources and technologies/tools.</li>\n <li>Describe plans to track potential impact of the proposed resources and technologies/tools.</li>\n <li>Describe plans to ensure the continued availability of the resources and technologies/tools to the research community.</li>\n <li>Include replication and validation plan for proposed models or related resources to be developed.</li>\n</ul>\n<p>Examples of resource-related projects suitable for this funding opportunity include, but are not limited to, development of mutant or transgenic models, NAMs, antibodies or other reagents, information resources, and informatics tools, and methods or tools for improving cryopreservation of genetic stocks, advancing techniques of regenerative medicine in models, and enhancing rigor and reproducibility of animal research. </p>"{"code":"NIH","seed":"HHS-NIH11","agencyCode":"HHS-NIH11","agencyName":"National Institutes of Health","topAgencyCode":"HHS"}359648[{"id":"23","description":"Small businesses"},{"id":"00","description":"State governments"},{"id":"01","description":"County governments"},{"id":"06","description":"Public and State controlled institutions of higher education"},{"id":"20","description":"Private institutions of higher education"},{"id":"22","description":"For profit organizations other than small businesses"},{"id":"07","description":"Native American tribal governments (Federally recognized)"},{"id":"11","description":"Native American tribal organizations (other than Federally recognized tribal governments)"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"}]"6""2025-06-09-00-00-00""Jun 09, 2025 03:33:00 PM EDT""2026-10-01-00-00-00""Jun 09, 2025 03:33:00 PM EDT""5000000""Sige Zou, PhD\r\nOffice of Research Infrastructure Programs (ORIP)""sige.zou@nih.gov""301-435-0749""2025-06-09-15-33-00"[{"id":"G","description":"Grant"}]"Dec 01, 2026 12:00:00 AM EST""sige.zou@nih.gov""2026-12-01-00-00-00""Sep 26, 2025 12:00:00 AM EDT""2025-09-26-00-00-00""5,000,000"[{"id":"HL","description":"Health"}]"Jan 25, 2026 12:00:00 AM EST""2026-01-25-00-00-00"0359648"D""Discretionary"{"id":429511,"revision":3,"cfdaNumber":"93.351","programTitle":"Research Infrastructure Programs","opportunityId":359648}22{"revision":2,"opportunityId":359648}"N""Dec 05, 2025 01:50:26 PM EST""U""HHS-NIH11"2027false"Jun 09, 2025 03:33:00 PM EDT""FON updated to reflect final NOFO prior to publication.""Jun 09, 2025 12:00:00 AM EDT""Oct 01, 2026 12:00:00 AM EDT""<p>The Division of Program Coordination, Planning and Strategic Initiatives, Office of Research Infrastructure Programs (<a href=\"https://orip.nih.gov/\" target=\"_blank\" style=\"color: rgb(31, 107, 178);\">ORIP</a>) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications aimed at developing, characterizing, or improving research models of human health and diseases; developing biology based new approach methodologies (NAMs); or improving access to information about or generated from the use of models of human disease. The models, including NAMs, and related biological materials developed must be broadly applicable to the scientific interests of two or more NIH Institutes or Centers (ICs) and must evaluate diseases and processes that impact multiple organ systems in order to align with the ORIP’s NIH-wide mission and programs. Applications must describe the need for and the potential impact of the proposed resources on the research community across a range of scientific disciplines supported by multiple NIH ICs.</p><p><br></p><p>This NOFO will utilize the R24 activity code to support research projects that will enhance the capability of resources to serve biomedical research. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. Details of the planned NOFO are provided below.</p><p><br></p><p><strong>Research Initiative Details</strong></p><p>ORIP’s intent with this NOFO is to support resource-related research projects aimed at developing and characterizing new model resources, improving existing resources, developing NAMs, or acquiring deep understanding of a model system to improve the utilization, accessibility, and translational value of experimental research models to the research community. An application may be predominantly research based if that research potentially leads to the development of tools or resources that will have a broad impact on the biomedical research community. An application also may be aimed at final development or enhancement of existing resources. Applications should:</p><ul> <li>Demonstrate the need for the proposed resources or technologies/tools.</li> <li>Address the impact, benefit, utilization, distribution, and accessibility of the proposed resources and technologies/tools.</li> <li>Describe plans to track potential impact of the proposed resources and technologies/tools.</li> <li>Describe plans to ensure the continued availability of the resources and technologies/tools to the research community.</li> <li>Include replication and validation plan for proposed models or related resources to be developed.</li></ul><p>Examples of resource-related projects suitable for this funding opportunity include, but are not limited to, development of mutant or transgenic models, NAMs, antibodies or other reagents, information resources, and informatics tools, and methods or tools for improving cryopreservation of genetic stocks, advancing techniques of regenerative medicine in models, and enhancing rigor and reproducibility of animal research. </p>"{"code":"NIH","seed":"HHS-NIH11","agencyCode":"HHS-NIH11","agencyName":"National Institutes of Health","topAgencyCode":"HHS"}359648[{"id":"23","description":"Small businesses"},{"id":"00","description":"State governments"},{"id":"01","description":"County governments"},{"id":"06","description":"Public and State controlled institutions of higher education"},{"id":"20","description":"Private institutions of higher education"},{"id":"22","description":"For profit organizations other than small businesses"},{"id":"07","description":"Native American tribal governments (Federally recognized)"},{"id":"11","description":"Native American tribal organizations (other than Federally recognized tribal governments)"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"}]"6""2025-06-09-00-00-00""Dec 05, 2025 01:31:04 PM EST""2026-10-01-00-00-00""Dec 05, 2025 01:31:04 PM EST""5000000""Sige Zou, PhD\r\nOffice of Research Infrastructure Programs (ORIP)""sige.zou@nih.gov""301-435-0749""2025-12-05-13-31-04"[{"id":"G","description":"Grant"}]"Dec 01, 2026 12:00:00 AM EST""sige.zou@nih.gov""2026-12-01-00-00-00""Sep 26, 2025 12:00:00 AM EDT""2025-09-26-00-00-00""5,000,000"[{"id":"HL","description":"Health"}]"Jan 25, 2026 12:00:00 AM EST""2026-01-25-00-00-00"2359648"D""Discretionary"{"id":429511,"revision":3,"cfdaNumber":"93.351","programTitle":"Research Infrastructure Programs","opportunityId":359648}{"id":431530,"revision":3,"opportunityId":359648}{"revision":3,"opportunityId":359648}13"Dec 24, 2025 10:16:00 AM EST""U""HHS-NIH11""none""Nov 02, 2028 12:00:00 AM EDT"false"Dec 05, 2025 01:50:26 PM EST""Dec 05, 2025 12:00:00 AM EST""none""Sep 28, 2028 12:00:00 AM EDT""The Office of Research Infrastructure Programs (ORIP) encourages grant applications aimed at developing, characterizing, or improving research models of human health and diseases; developing biology based new approach methodologies (NAMs) applicable to human health and diseases; or improving access to information about or generated from the use of models of human disease. The models, including NAMs, and related biological materials developed must be broadly applicable to the scientific interests of two or more NIH Institutes or Centers (ICs) and must evaluate diseases and processes that impact multiple organ systems in order to align with the ORIP\"s NIH-wide mission and programs. Applications must describe the need for and the potential impact of the proposed resources on the research community across a range of scientific disciplines supported by multiple NIH ICs. Applications to develop models that relate strictly to a specific disease or a select area of research or that do not have a broad impact on the NIH-wide research community will not be accepted. Projects that predominantly address the research interests of one NIH IC but are only peripherally related to the research interests of other ICs will also not be accepted, if submitted in response to this notice of funding opportunity (NOFO)."{"code":"NIH","seed":"HHS-NIH11","agencyCode":"HHS-NIH11","agencyName":"National Institutes of Health","topAgencyCode":"HHS"}359648[{"id":"25","description":"Others (see text field entitled \"Additional Information on Eligibility\" for clarification)"},{"id":"23","description":"Small businesses"},{"id":"00","description":"State governments"},{"id":"02","description":"City or township governments"},{"id":"01","description":"County governments"},{"id":"06","description":"Public and State controlled institutions of higher education"},{"id":"20","description":"Private institutions of higher education"},{"id":"13","description":"Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"22","description":"For profit organizations other than small businesses"},{"id":"07","description":"Native American tribal governments (Federally recognized)"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"}]"2028-11-02-00-00-00""6""2025-12-05-00-00-00""Dec 05, 2025 01:50:37 PM EST""Dec 05, 2025 01:50:26 PM EST""2028-09-28-00-00-00""5000000""ORIPDCM@mail.nih.gov""Office of Research Infrastructure Programs (ORIP)\nORIPDCM@mail.nih.gov""National Institutes of Health""ORIPDCM@mail.nih.gov""301-402-2541""2025-12-05-13-50-37"[{"id":"G","description":"Grant"}]"ORIPDCM@mail.nih.gov""Refer to Section III. Eligibility Information of the NOFO for additional information on eligibility.Foreign Organizations/Foreign CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.""5,000,000"[{"id":"HL","description":"Health"}]3359648"D""Discretionary"{"id":349818,"fileName":"RFA-OD-25-010-Full-Announcement.html","mimeType":"text/html;charset=ISO-8859-1","createdDate":"Dec 05, 2025 01:50:37 PM EST","fileLobSize":115434,"opportunityId":359648,"fileDescription":"RFA-OD-25-010-Full-Announcement.html","synopsisAttFolderId":78644}{"id":349954,"fileName":"RFA-OD-25-010-Revised-Full-Announcement.html","mimeType":"text/html;charset=ISO-8859-1","createdDate":"Dec 24, 2025 10:16:04 AM EST","fileLobSize":114253,"opportunityId":359648,"fileDescription":"RFA-OD-25-010-Revised-Full-Announcement.html","synopsisAttFolderId":78700}Source: Grants.gov (opportunity GRANTS-359648), retrieved via the Grants.gov Search API. View the official posting — always confirm requirements and deadlines with the issuing agency.
Here are some similar opportunities
Let our AI help you find the right opportunity
Search with AI →