The purpose of this notice of funding opportunity (NOFO) is to support research on interventions to improve health in Native American (NA) populations. This includes 1) etiologic research, where there is a significant gap in knowledge, that will directly inform intervention development or adaptations, 2) research that develops, adapts, or tests the efficacy or effectiveness of health promotion and disease prevention interventions, 3) research that tests culturally informed treatment or recovery interventions and 4) where a sufficient body of knowledge on intervention efficacy exists, research on dissemination and implementation that develops and tests strategies to overcome barriers to the adoption, integration, scale-up, and sustainability of effective interventions. Existing data suggest that significant acute and chronic disease inequities exist for NA populations.
Concurrently, NA populations experience unique sociopolitical, historical, and environmental stressors and risks that may exacerbate health conditions and/or impact the effectiveness of existing solutions to address the conditions. They also possess unique strengths and resiliencies that can mitigate stressors or inform intervention strategies. Through this initiative, intervention and related research is sought to build upon community knowledge, resources, and resilience to test science-based, culturally appropriate solutions to reduce morbidity and mortality through identification and remediation of precursors to diseases and disorders and through culturally informed treatment.
Interventions should be designed with a consideration for sustainability within the communities where they are tested, and have the flexibility to be readily adapted, disseminated, and scaled up to other communities where culturally appropriate. For the purposes of this NOFO, NA includes the following populations: Alaska Natives, American Indians (whose ancestral lands fall at least partially within the U.S. main land).
"05""Independent school districts""00""State governments""25""Others (see text field entitled \"Additional Information on Eligibility\" for clarification)""07""Native American tribal governments (Federally recognized)""06""Public and State controlled institutions of higher education""13""Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education""23""Small businesses""01""County governments""20""Private institutions of higher education""22""For profit organizations other than small businesses""12""Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education""04""Special district governments""02""City or township governments""11""Native American tribal organizations (other than Federally recognized tribal governments)""08""Public housing authorities/Indian housing authorities""G""Grant""ED""Education""ENV""Environment""HL""Health""ISS""Income Security and Social Services""NIH""HHS-NIH11""HHS-NIH11""National Institutes of Health""HHS""HHS""HHS""HHS""Department of Health and Human Services""HHS"{"id":427519,"revision":1,"cfdaNumber":"93.113","programTitle":"Environmental Health","opportunityId":358373}{"id":427516,"revision":1,"cfdaNumber":"93.121","programTitle":"Oral Diseases and Disorders Research","opportunityId":358373}{"id":427523,"revision":1,"cfdaNumber":"93.213","programTitle":"Research and Training in Complementary and Integrative Health","opportunityId":358373}{"id":427524,"revision":1,"cfdaNumber":"93.242","programTitle":"Mental Health Research Grants","opportunityId":358373}{"id":427517,"revision":1,"cfdaNumber":"93.273","programTitle":"Alcohol Research Programs","opportunityId":358373}{"id":427520,"revision":1,"cfdaNumber":"93.279","programTitle":"Drug Use and Addiction Research Programs","opportunityId":358373}{"id":427514,"revision":1,"cfdaNumber":"93.310","programTitle":"Trans-NIH Research Support","opportunityId":358373}{"id":427521,"revision":1,"cfdaNumber":"93.313","programTitle":"NIH Office of Research on Women's Health","opportunityId":358373}{"id":427522,"revision":1,"cfdaNumber":"93.361","programTitle":"Nursing Research","opportunityId":358373}{"id":427518,"revision":1,"cfdaNumber":"93.865","programTitle":"Child Health and Human Development Extramural Research","opportunityId":358373}{"id":427515,"revision":1,"cfdaNumber":"93.866","programTitle":"Aging Research","opportunityId":358373}{"id":427525,"revision":1,"opportunityId":358373}{"revision":0,"opportunityId":358373}10"Mar 26, 2025 09:15:01 AM EDT""U""HHS-NIH11""none""Feb 12, 2027 12:00:00 AM EST"false"Jan 22, 2025 10:46:05 AM EST""Jan 22, 2025 12:00:00 AM EST""none""Jan 07, 2027 12:00:00 AM EST""The purpose of this notice of funding opportunity (NOFO) is to support research on interventions to improve health in Native American (NA) populations. This includes 1) etiologic research, where there is a significant gap in knowledge, that will directly inform intervention development or adaptations, 2) research that develops, adapts, or tests the efficacy or effectiveness of health promotion and disease prevention interventions, 3) research that tests culturally informed treatment or recovery interventions and 4) where a sufficient body of knowledge on intervention efficacy exists, research on dissemination and implementation that develops and tests strategies to overcome barriers to the adoption, integration, scale-up, and sustainability of effective interventions. Existing data suggest that significant acute and chronic disease inequities exist for NA populations. Concurrently, NA populations experience unique sociopolitical, historical, and environmental stressors and risks that may exacerbate health conditions and/or impact the effectiveness of existing solutions to address the conditions. They also possess unique strengths and resiliencies that can mitigate stressors or inform intervention strategies. Through this initiative, intervention and related research is sought to build upon community knowledge, resources, and resilience to test science-based, culturally appropriate solutions to reduce morbidity and mortality through identification and remediation of precursors to diseases and disorders and through culturally informed treatment. Interventions should be designed with a consideration for sustainability within the communities where they are tested, and have the flexibility to be readily adapted, disseminated, and scaled up to other communities where culturally appropriate. For the purposes of this NOFO, NA includes the following populations: Alaska Natives, American Indians (whose ancestral lands fall at least partially within the U.S. main land)."{"code":"NIH","seed":"HHS-NIH11","agencyCode":"HHS-NIH11","agencyName":"National Institutes of Health","topAgencyCode":"HHS"}358373[{"id":"20","description":"Private institutions of higher education"},{"id":"05","description":"Independent school districts"},{"id":"04","description":"Special district governments"},{"id":"01","description":"County governments"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"02","description":"City or township governments"},{"id":"13","description":"Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"11","description":"Native American tribal organizations (other than Federally recognized tribal governments)"},{"id":"06","description":"Public and State controlled institutions of higher education"},{"id":"23","description":"Small businesses"},{"id":"00","description":"State governments"},{"id":"22","description":"For profit organizations other than small businesses"},{"id":"07","description":"Native American tribal governments (Federally recognized)"},{"id":"25","description":"Others (see text field entitled \"Additional Information on Eligibility\" for clarification)"},{"id":"08","description":"Public housing authorities/Indian housing authorities"}]"2027-02-12-00-00-00""2025-01-22-00-00-00""Jan 22, 2025 10:55:33 AM EST""Jan 22, 2025 10:46:05 AM EST""2027-01-07-00-00-00""See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.""NIH Grants Information\ngrantsinfo@nih.gov""National Institutes of Health""grantsinfo@nih.gov""301-402-2541""2025-01-22-10-55-33""http://grants.nih.gov/grants/guide/pa-files/PAR-25-378.html"[{"id":"G","description":"Grant"}]"https://grants.nih.gov/grants/guide/pa-files/PAR-25-378.html""See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.""Other Eligible Applicants include the following:\n Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.\n\nNon-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.\n\nForeign components, as defined in the NIH Grants Policy Statement, are allowed."[{"id":"ED","description":"Education"},{"id":"ENV","description":"Environment"},{"id":"HL","description":"Health"},{"id":"ISS","description":"Income Security and Social Services"}]0358373"D""Discretionary"{"id":427519,"revision":1,"cfdaNumber":"93.113","programTitle":"Environmental Health","opportunityId":358373}{"id":427516,"revision":1,"cfdaNumber":"93.121","programTitle":"Oral Diseases and Disorders Research","opportunityId":358373}{"id":427523,"revision":1,"cfdaNumber":"93.213","programTitle":"Research and Training in Complementary and Integrative Health","opportunityId":358373}{"id":427524,"revision":1,"cfdaNumber":"93.242","programTitle":"Mental Health Research Grants","opportunityId":358373}{"id":427517,"revision":1,"cfdaNumber":"93.273","programTitle":"Alcohol Research Programs","opportunityId":358373}{"id":427520,"revision":1,"cfdaNumber":"93.279","programTitle":"Drug Use and Addiction Research Programs","opportunityId":358373}{"id":427514,"revision":1,"cfdaNumber":"93.310","programTitle":"Trans-NIH Research Support","opportunityId":358373}{"id":427521,"revision":1,"cfdaNumber":"93.313","programTitle":"NIH Office of Research on Women's Health","opportunityId":358373}{"id":427522,"revision":1,"cfdaNumber":"93.361","programTitle":"Nursing Research","opportunityId":358373}{"id":427518,"revision":1,"cfdaNumber":"93.865","programTitle":"Child Health and Human Development Extramural Research","opportunityId":358373}{"id":427515,"revision":1,"cfdaNumber":"93.866","programTitle":"Aging Research","opportunityId":358373}{"id":427525,"revision":1,"opportunityId":358373}{"revision":1,"opportunityId":358373}21"N""May 22, 2025 01:44:01 PM EDT""U""HHS-NIH11""none""Mar 27, 2025 12:00:00 AM EDT"false"Jan 22, 2025 10:46:05 AM EST""Closed""Jan 22, 2025 12:00:00 AM EST""none""Mar 26, 2025 12:00:00 AM EDT""<p>Not available</p>"{"code":"NIH","seed":"HHS-NIH11","agencyCode":"HHS-NIH11","agencyName":"National Institutes of Health","topAgencyCode":"HHS"}358373[{"id":"20","description":"Private institutions of higher education"},{"id":"05","description":"Independent school districts"},{"id":"04","description":"Special district governments"},{"id":"01","description":"County governments"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"02","description":"City or township governments"},{"id":"13","description":"Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"11","description":"Native American tribal organizations (other than Federally recognized tribal governments)"},{"id":"06","description":"Public and State controlled institutions of higher education"},{"id":"23","description":"Small businesses"},{"id":"00","description":"State governments"},{"id":"22","description":"For profit organizations other than small businesses"},{"id":"07","description":"Native American tribal governments (Federally recognized)"},{"id":"25","description":"Others (see text field entitled \"Additional Information on Eligibility\" for clarification)"},{"id":"08","description":"Public housing authorities/Indian housing authorities"}]"2025-03-27-00-00-00""2025-01-22-00-00-00""Mar 26, 2025 09:15:09 AM EDT""Mar 26, 2025 09:15:01 AM EDT""2025-03-26-00-00-00""See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.""NIH Grants Information\r\ngrantsinfo@nih.gov""National Institutes of Health""grantsinfo@nih.gov""301-402-2541""2025-03-26-09-15-09""http://grants.nih.gov/grants/guide/pa-files/PAR-25-378.html"[{"id":"G","description":"Grant"}]"https://grants.nih.gov/grants/guide/pa-files/PAR-25-378.html""See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.""Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed."[{"id":"ED","description":"Education"},{"id":"ENV","description":"Environment"},{"id":"HL","description":"Health"},{"id":"ISS","description":"Income Security and Social Services"}]1358373"D""Discretionary"{"id":347948,"fileName":"PAR-25-378-Full-Announcement.html","mimeType":"text/html","createdDate":"Jun 02, 2025 11:23:02 AM EDT","fileLobSize":422,"opportunityId":358373,"fileDescription":"PAR-25-378 Full Announcement Text","synopsisAttFolderId":77783}Source: Grants.gov (opportunity GRANTS-358373), retrieved via the Grants.gov Search API. 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