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NIMH seeks applications for pilot effectiveness projects to evaluate the preliminary effectiveness of therapeutic and service delivery interventions for the post-acute management of mental health conditions that are matched to the stage of illness in terms of both their focus (e.g., consolidating and maintaining gains from initial treatment, managing residual symptoms/impairment, preventing relapse, promoting adherence and appropriate service use) and intensity/burden. In this pilot phase of effectiveness research, the trial should be designed to evaluate the feasibility, tolerability, acceptability, safety, and potential effectiveness of the approach; to address whether the intervention engages the target(s)/mechanisms(s) that is/are presumed to underlie the intervention effects; and to obtain preliminary data needed as a pre-requisite to a larger-scale effectiveness trial (e.g., comparative effectiveness study, practical trial) designed to definitely test the effectiveness of interventions to improve post-acute outcomes. This Notice of Funding Opportunity (NOFO) supports pilot effectiveness research to evaluate the feasibility, tolerability, acceptability, safety and preliminary indications of effectiveness of post-acute phase intervention approaches and inform the design of definitive effectiveness trials.
Support for fully-powered, definitive effectiveness studies focused on post-acute phase interventions is provided via the R01 currently TEMP-24813.
"06""Public and State controlled institutions of higher education""00""State governments""01""County governments""12""Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education""02""City or township governments""04""Special district governments""05""Independent school districts""08""Public housing authorities/Indian housing authorities""11""Native American tribal organizations (other than Federally recognized tribal governments)""13""Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education""07""Native American tribal governments (Federally recognized)""20""Private institutions of higher education""22""For profit organizations other than small businesses""23""Small businesses""25""Others (see text field entitled \"Additional Information on Eligibility\" for clarification)""G""Grant""HL""Health""NIH""HHS-NIH11""HHS-NIH11""National Institutes of Health""HHS""HHS""HHS""HHS""Department of Health and Human Services""HHS"{"id":343723,"fileName":"PAR-25-206-Full-Announcement.html","mimeType":"text/html","createdDate":"Oct 31, 2024 01:48:29 PM EDT","fileLobSize":422,"opportunityId":356923,"fileDescription":"PAR-25-206 Full Announcement Text","synopsisAttFolderId":75110}Source: Grants.gov (opportunity GRANTS-356923), retrieved via the Grants.gov Search API. View the official posting — always confirm requirements and deadlines with the issuing agency.
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