Department of Health and Human ServicesIssuing agency·Maryland·via the SAM.gov Get Opportunities APIWe'll email you new uncategorized opportunities in Maryland as agencies publish them — free, unsubscribe whenever.
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(i)This is a combined synopsis/solicitation for commercial items prepared in accordancewith the format in FAR Subpart 12.6, as supplemented with additional information includedin this notice. This announcement constitutes the only solicitation; proposals are beingrequested, and a separate written solicitation will not be issued.
(ii)The solicitation number is 75N98027Q00007. This solicitation is issued as a Notice ofIntent (NOI) for a non-competitive combined synopsis/solicitation to award a contract orpurchase order without providing for full and open competition (including brand-name, ifapplicable).
This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services, and is not expected to exceed the simplified acquisition threshold. Additional authority includes 41 U.S.C. 1901 and FAR 6.302-3(a)(2)(ii).
The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, intends to negotiate and award a firm-fixed-price purchase order on a non-competitive basis to University of Alabama at Birmingham, 701 S 20th Street, Birmingham, AL 35294-0001-0001, for research support to develop and validate circulating cell-free DNA (cfDNA) as a blood-based biomarker of chlorine-induced acute lung injury, using the Matalon Laboratory's sole-source validated murine chlorine inhalation injury model, established mechanistic expertise, access to its actively enrolling aspiration pneumonitis biorepository (human proxy cohort), existing collaborative infrastructure with the NHLBI Laboratory of Precision Omics, and continuity with peer-reviewed federal funding (NIH R01 HL031197). These capabilities are not available from any other source and are essential to the project's feasibility.
(iii)The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2026-01, effective 03/13/2026.
(iv)The associated NAICS code is 541380, Testing Laboratories and Services, and the small business size standard is $19.0 million. This requirement is not set aside for small business.
The requirement encompasses use of the established murine chlorine exposure model and associated mechanistic groundwork, access to the actively enrolling aspiration pneumonitis biorepository serving as the human proxy cohort, existing collaborative infrastructure, and continuity with peer-reviewed federal funding. Work includes exposure of equal numbers of male and female mice to Cl2 gas and evaluation of acute lung injury post-exposure, including measurement of bronchoalveolar lavage protein content and cell counts, plasma cytokines/chemokines, lung injury histology scoring, lung edema (wet-to-dry weight ratio), blood gases, epithelial sodium channel activity, alveolar fluid clearance, hemopexin and heme quantitation, and lung mitochondrial DNA concentration and DNA lesion analysis, as described in the Government's statement of work.
"20201""Washington""DC""US""Hubert H. Humphrey Building 200 Independence Avenue, SW ""20892""Bethesda""MD""US""3100 Center Drive Room 1B59""20892""BETHESDA""MD""USA""6011 EXECUTIVE BLVD., SUITE 503L""Sol_75N98027Q00007.pdf"284346"file"".pdf""1""2026-10-13T12:10:31.977+00:00""817a553017fb49bf9062ccb309d2722b""public""0""public""9e1391708772479e860f062e05d97fa7""0"1"0"Most Maryland work asks for the two below, and the solicitation documents are where it’s stated. One prequalification covers both — on this bid and the next.
A surety’s written statement that it expects to bond you up to a stated amount, subject to final underwriting. It’s what a GC or agency asks to see before they take your bid seriously.
Source: SAM.gov (notice 66af16818b144456af1ddc0d52fc9378), retrieved via the SAM.gov Get Opportunities API. View the official posting, and always confirm requirements and deadlines with the issuing agency.