The Advanced Research Projects Agency for Health (ARPA-H) Comprehensive Organ System Modeling in Outer Space (COSMOS) Initiative aims to definitively prove or disprove if exposure to microgravity in Low Earth Orbit (LEO) truly accelerates tissue aging across brain, cardiac, uterine, and kidney tissue types and across several adult age brackets. Provided Tissue Aging Rate in Space (TARIS) exceeds Tissue Aging Rate on Earth (TAROE) at a rate that exceeds the on Earth breakeven cost for new drug R&D, COSMOS will create a first-in-class platform for fully autonomous, high-throughput drug screening in LEO that would be more cost effective and faster than new drug R&D on Earth.
ARPA-H anticipates multiple Other Transaction awards resulting from this announcement.
Interested parties are invited to download and review the attached COSMOS Innovative Solutions Opening (ISO) ARPA-H-SOL-26-165
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"20201""Washington""DC""US""Hubert H. Humphrey Building 200 Independence Avenue, SW ""20892""Bethesda""MD""US""3100 Center Drive Room 1B59""208920004""Bethesda""MD""USA""BG NIHBC 01 Room 228""1 Center Drive""Attachment E_COSMOS Administrative and National Policy Requirements.docx"97684"file"".docx""1""2026-09-16T19:17:13.811+00:00""4249cfb685fc45908b02847b13094000""public""0""public""6bc54516a20c4b9194453a6f7e5c86ef""0"8"0""ATTACHMENT A.1_Technical & Management Proposal Model (VOL I).docx"56227"file"".docx""1""2026-09-16T19:17:13.811+00:00""e1208b36c5354eb8a9205ef41b35730c""public""0""public""b52cda37ae9b49a291b83884de34a971""0"7"0""Attachment D_COSMOS Cost Proposal Template.xlsx"149024"file"".xlsx""1""2026-09-16T19:17:13.811+00:00""3bffd79ec8644ff5a478dc5e5a60e0c2""public""0""public""6d6737098d6346d088a1fc406118dc8f""0"6"0""ATTACHMENT A.2_Task Description Document Model.docx"43509"file"".docx""1""2026-09-16T19:17:13.811+00:00""42c5c638fedb4caca948f380a393f560""public""0""public""9a8b70ac614547949ce9ac93ad2401d4""0"5"0""ATTACHMENT B_COSMOS Eligibility and Conformance Certification Sheet.docx"36557"file"".docx""1""2026-09-16T19:17:13.811+00:00""0bcc046159444a71985b08eb41da892c""public""0""public""da61523d1c2c4783bf5ac06ec7c59654""0"4"0""ATTACHMENT C COSMOS Schedule.xlsx"20898"file"".xlsx""1""2026-09-16T19:17:13.811+00:00""bb7c5c3bce3a4ebf9842cedc745abade""public""0""public""acd04b37c7424ddcafc08f928bd3f827""0"3"0""ATTACHMENT A.3_COSMOS Milestone and Payment Table.xlsx"22307"file"".xlsx""1""2026-09-16T19:17:13.811+00:00""f0acc10b4dcb42babcd3c651e8ee1469""public""0""public""8b5aeeeeeec345d09aa497183a3aa372""0"2"0""ARPA-H-SOL-26-165_COSMOS_ISO.docx"912947"file"".docx""1""2026-09-16T19:17:13.811+00:00""08aa48d885fc42bf86957b0a03e8c61c""public""0""public""84c9c688537d4f7382e58a51edaf1867""0"1"0"Most Washington, DC work asks for the two below, and the solicitation documents are where it’s stated. Here’s what each costs through Light RFP if you need one.
Source: SAM.gov (notice f7ed4368bf8c48e39ca45d3204830c25), retrieved via the SAM.gov Get Opportunities API. View the official posting, and always confirm requirements and deadlines with the issuing agency.