Presolicitation notice (sole source) for acquisit

The Department of the Interior, Interior Business Center (IBC), on behalf of the National Institutes of Health (NIH), National Cancer Institute (NCI), Center for Cancer Research (CCR), intends to procure an Oxford Nanopore PromethION 2 Integrated (P2i) Long-read Sequencing Platform. The sequencing system is required to support CCR Genomics Core operations that provide long-read genomic sequencing services essential to intramural cancer research programs. The PromethION 2 Integrated platform provides advanced long-read DNA and RNA sequencing capabilities, real-time analysis, integrated GPU-accelerated basecalling, modified base detection, and full compatibility with existing ONT PromethION flow cells and validated CCR workflows. The CCR Genomics Core requires an upgrade from its current PromethION 2 Solo (P2 Solo) instrument, which relies on external compute hardware. The P2i integrates sequencing and high-performance compute into a single platform, reducing workflow complexity, eliminating external workstation dependencies, decreasing turnaround time, and supporting high-throughput sequencing operations for structural variant analysis, epigenetic profiling, transcriptomic characterization, and de novo genome assembly research.