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The gene therapy manufacturing innovations in measurement sciences (IMS) project, in the Biosystems and Biomaterials Division, within the Material Measurement Laboratory of the National Institute of Standards and technology, pursues the goal of developing light scattering microscopy methods to characterize gene delivery particles. Emerging gene therapy treatments use gene delivery nanoparticles, such as viral vectors and non-viral carriers, to cure intractable diseases. These manufactured particles suffer heterogeneity issues that hinder treatment efficacy and safety.
This project aims to develop light-scattering microscopy methods to enable rapid, multi-attribute measurements of individual gene therapy nanoparticles’ physical characteristics. Such measurements will speed the development of new gene therapy treatments and improve their efficacy and safety.
The contractor shall provide one (1) high-speed camera system and one (1) set of user operation and maintenance manuals meeting minimum technical requirements, including high-speed imaging at 2,166 fps at full 3.6 MP resolution, selectable gain modes, integrated liquid cooling, and compatibility with pco.camware software. Delivery is F.O.B. Destination within 120 calendar days of award, and a one-year warranty covering parts, labor, and travel is required.
"US""US""20899""GAITHERSBURG""MD""USA""ACQUISITION MANAGEMENT DIVISION""100 BUREAU DR.""Attachment 2- Applicable Provisions and Clauses.docx"53725"file"".docx""1""2026-08-05T02:49:22.426+00:00""21ef72b0068b4f97bee60cf5b98a13a6""public""0""public""650df46622d44359ad9032d88bb85602""0"3"0""Solicitation_1333ND26QNB640413.docx"46230"file"".docx""1""2026-08-05T02:49:22.426+00:00""2f840d6205a34243b01d54f5065de438""public""0""public""0d4f9c55fc1c4db38548f83cc9d5aa02""0"2"0""Ultrafast Microscope Camera -7-29-2026.docx"29964"file"".docx""1""2026-08-05T02:49:22.426+00:00""71c809a12d2a40538be03082217140af""public""0""public""5e2dbfa636fa4a6b94f82e866987cd72""0"1"0"Source: SAM.gov (notice 943ff888d6fe4d4c8eb299e603fa5301), retrieved via the SAM.gov Get Opportunities API. View the official posting , always confirm requirements and deadlines with the issuing agency.