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The gene therapy manufacturing innovations in measurement sciences (IMS) project, in the Biosystems and Biomaterials Division, Material Measurement Laboratory, National Institute of Standards and Technology, aims to develop light scattering microscopy methods to characterize gene delivery particles. Emerging gene therapy treatments use gene delivery nanoparticles, such as viral vectors and non-viral carriers, to cure intractable diseases. These manufactured particles suffer heterogeneity issues that hinder treatment efficacy and safety.
This project aims to develop light-scattering microscopy methods to enable rapid, multi-attribute measurements of individual gene therapy nanoparticles’ physical characteristics, speeding the development of new treatments and improving their efficacy and safety.
The contractor shall provide one Oxford Instruments Andor CB2-HS-0.5 scientific CMOS camera (or equivalent) meeting minimum technical requirements including a 0.5 Megapixel sCMOS sensor, global shutter, CoaXPress interface, and a combined performance metric of at least 2368 ke-/(μm²·s). The contractor shall also provide one set of user operations and maintenance manuals, and a 12-month Customer Assurance Service Plan covering priority support, LiveAssist, and repairs. Delivery shall be F.O.B. Destination within 120 calendar days of award to NIST in Gaithersburg, MD.
"US""US""20899""GAITHERSBURG""MD""USA""ACQUISITION MANAGEMENT DIVISION""100 BUREAU DR.""Attachment 2- Applicable Provisions and Clauses_Flow Sorter.docx"54440"file"".docx""1""2026-08-09T23:06:19.034+00:00""5228e51685d3448fac16bbd3adfabc7b""public""0""public""2f6c8e9919a449d599cd20bba5150188""0"3"0""Solicitation_1333ND26QNB640412 - 7-29-2026.docx"45660"file"".docx""1""2026-08-09T23:06:19.034+00:00""346d13f9b2e44598be30b08c0a00278f""public""0""public""26c9346b0a9a4f02beaa14e5d3d9ba65""0"2"0""26-01524_Microscope Camera SOR Instrument-7-29-2026.docx"32754"file"".docx""1""2026-08-09T23:06:19.034+00:00""40cd84ac0ca04504903d76cbd9a8eb6e""public""0""public""f3004b1905ea45b5aea44ed16e3214a9""0"1"0"Source: SAM.gov (notice 81c38fb81ab54bbeb7c0bb1b492ea9c1), retrieved via the SAM.gov Get Opportunities API. View the official posting , always confirm requirements and deadlines with the issuing agency.