Olink Explorer >5400

Requirements:

2.0 BACKGROUND

*Our lab studies the role of inflammation/innate resistance and commensal microbiota in carcinogenesis, cancer progression and therapy of cancer. *

*The following product features/characteristics are required for this requirement: *

**Protein Coverage - **Measures ~5,400+ human proteins simultaneously in a single workflow.

Technology - Uses Proximity Extension Assay (PEA)*** with dual antibody recognition coupled to DNA barcoding and next-generation sequencing (NGS) readout.*

**Sample input – **requires only 2 ul of plasma, serum, and other sample types

Specificity* - Reported 99.5% specificity with negligible cross-reactivity due to dual-recognition antibody design.*

Dynamic Range* - Approximately 10 orders of magnitude (fg/mL to mg/mL****)***, enabling detection of both low- and high-abundance proteins.

Key strengths

• *Very broad proteome coverage while maintaining antibody-based specificity. *

• *Excellent sensitivity for low-abundance circulating proteins (especially cytokines and signaling proteins). *

• *Extremely low sample-volume requirement. *

• Highly standardized platform, making it attractive for epidemiology and multi-omics studies.